Monday, October 10, 2016

What is HSAN-IV?


Congenital insensitivity to pain with anhidrosis (CIPA), also called hereditary sensory and autonomic neuropathy type IV (HSAN-IV), which is characterized by its inability to feel pain and temperature, and decreased or absence sweating which often leads to repeated severe injuries (“Genetics Home Reference- CIPA”, 2016). 

However, patients with CIPA can still feel pressure. CIPA is the fourth type of hereditary sensory and autonomic neuropathy which is a rare recessive gene disorder caused by gene mutation. A person with CIPA cannot feel pain or differentiate even extreme temperatures. By interpreting its name, "anhidrosis" means the body does not sweat, and "congenital" indicates that the condition is present from birth. Therefore, this also explains why signs and symptoms of CIPA appear early, usually at birth or during infancy.  

Read more herehttps://ghr.nlm.nih.gov/condition/congenital-insensitivity-to-pain-with-anhidrosis#definition





Reference: 
U.S. National Library of Medicine. (2016). Congenital insensitivity to pain with anhidrosis.    U.S. National Library of Medicine. Retrieved October 13, 2016 from  https://ghr.nlm.nih.gov/condition/congenital-insensitivity-to-pain-with-anhidrosis#definition



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